(Translated by https://www.hiragana.jp/)
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8 Chemical Interpretation is not possible for this label d k w Total synthesis of Repraesentin F and Configuration Reassignment by a Gold(I)-Catalyzed Cyclization Cascade 5 : ̬, :,8 |
8 Chemical Interpretation is not possible for this label & Ferrer, S., Echavarren, A.
G - `> - J bι
8 Chemical Interpretation is not possible for this label f
Org.Lett, 2018, 20, 57845788) y c ̌p c | @}
8 Chemical Interpretation is not possible for this label PTSA M MY
8 Chemical Interpretation is not possible for this label I 10:1 acetone/H2O
70 C @ @r L @rL @n
8 Chemical Interpretation is not possible for this label 3 KOtBu, 18-crown-6
THF, -78 C + @ L L h
8 Chemical Interpretation is not possible for this label $ N ` " # 1. TBSOTf, Et3N
Et2O, 0 to 25 C - , # ̌E|(
8 Chemical Interpretation is not possible for this label * T ` " ) 2. Et2Zn, CH2I2
CH2Cl2
-60 to 0 C @ L "
E@
8 Chemical Interpretation is not possible for this label ? ` 1. K2CO3, MeOH, 25 C ) 7&2
8 Chemical Interpretation is not possible for this label Q ` 2. nBuLi THF, -78 C
Ac2O = z i q i @
8 Chemical Interpretation is not possible for this label ) ` Et2O
40C ? @X
LO
ZJ
8 Chemical Interpretation is not possible for this label cat. 0.5 mol % ̪ sb
] 8 Chemical Interpretation is not possible for this label F ` 1. Pd/C, H2
AcOEt, 45 C ̌ h)
^ 8 Chemical Interpretation is not possible for this label
\
2. LiAlH4
Et2O, 0 to 25 C p @ L L
& ChemDraw can't interpret this label. ` SnBu2O
TsCl, Et3N q @ @"
8 Chemical Interpretation is not possible for this label - ` Ch2Cl2, 25 C u v m ̄*G
8 Chemical Interpretation is not possible for this label $
THF
0 to 25 C X O f jR
/ 8 Chemical Interpretation is not possible for this label " 8 ! 1. TBSCl, imidazole
DMF, 70 C | s w7j
0 8 Chemical Interpretation is not possible for this label / Y ` - . 2. Dess-Martin periodane
CH2Cl2, 0 to 25 C @ @ Y
8 Chemical Interpretation is not possible for this label
* TBAF, THF
0 to 25 C R Z y ̌Q y fJ
D 8 Chemical Interpretation is not possible for this label * 0 P * Grennari modification of HornerWadsworthEmmons S \ S ̌^S>
E 8 Chemical Interpretation is not possible for this label 4 SimmonsSmith cyclopropanation T @ @ ̌@
F 8 Chemical Interpretation is not possible for this label % concomitant epimerization U t k Lws
G 8 Chemical Interpretation is not possible for this label & gold catalyzed cyclization Z H `x > `x J]
L 8 Chemical Interpretation is not possible for this label repraesentin F [ ` ` l ` 5
M 8 Chemical Interpretation is not possible for this label 52% over two steps \ ` ` l ` e
N 8 Chemical Interpretation is not possible for this label 81% ] `R w lIlgl`
O 8 Chemical Interpretation is not possible for this label 89%
6:1 Z:E ^ X `J ,O `J̬Z ǡ
P 8 Chemical Interpretation is not possible for this label 85% over two steps _ X ,O ̬Z
Q 8 Chemical Interpretation is not possible for this label 68% over two steps ` p , p ̬
R 8 Chemical Interpretation is not possible for this label 72% (main product) a r , r̬
S 8 Chemical Interpretation is not possible for this label 49% over two steps b T , T̬
T 8 Chemical Interpretation is not possible for this label 63% (main product) c ` ̬ `,
U 8 Chemical Interpretation is not possible for this label 56% (main product) d p ̬ p , G
V 8 Chemical Interpretation is not possible for this label 84% over two steps P P `E
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